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As we only use innovative procedures in our dental office in Mexico, we routinely use platelet rich plasma (PRP) in oral surgeries that involve hard and soft tissues, derived from the patient.
PRP preparations have been proposed for several uses in dental and oral surgery. The ease with which these preparations are used might be helpful to the dental professional in many surgical procedures, and their safety might encourage their wide employment.
The use PRP in the alveolar socket after tooth extractions is certainly able to improve soft tissue healing and positively influence bone regeneration but this latter effect seems to decrease a few days after extraction. PRP has revealed better results in periodontal therapy in association with other materials than when it is used alone, suggesting that the specific selection of agents/procedures combined with PRP could be important.
Promising results have also been obtained in implant surgery, using PRP on its own as a coating material. Furthermore, the combination of PRP application with other biomaterials seems to be favorable as regards sinus lifting even if the choice of material used is critical in this field. The combination of necrotic bone curettage and PRP application seem to be encouraging for the treatment it has demonstrated successful outcomes with minimal invasively.
Recently, PRP has become a valuable adjunct to promote healing in many procedures in dental and oral surgery. They include: ablative surgical procedures, mandibular reconstruction and surgical repair of the alveolar cleft, treatment of infrabony periodontal defects and periodontal plastic surgery, as well as procedures relating to the placement of osseo integrated implants. In such procedures, the adhesive nature of PRP facilitates the easier handling of graft material, with more predictable flap adaptation and hemostasis, and a more predictable seal than is the case with primary closure alone.
Recently, the use of PRP has also been proposed in the management of bisphosphonate-related osteonecrosis of the jaw (BRONJ) or avascular necrosis, which is caused by other factors (e.g. radio-osteonecrosis), with the aim of increasing wound healing and bone maturation.
The growth factors present in PRP are capable of forming a fibrin clot, promoting fibroblast proliferation and up-regulating collagen synthesis in the extracellular matrix. Thus, the use of PRP at injury sites might be able to promote wound healing and the regeneration of periodontal soft tissues. Moreover, the ability of these factors to accelerate bone repair by increasing the mitosis of osteoblasts and tissue vascularity might be useful in the treatment of infra-bony defects.
If you have any questions about treatment with platelet rich plasma or would like to find out if you are a candidate and can benefit from this treatment, please contact our dental office in Tijuana today to schedule an appointment.